What major deal did AstraZeneca finalize regarding AI development in life sciences?

AstraZeneca signed a $555 million deal to develop new drugs, signaling a strategic shift toward using processing cores as a catalyst for R&D rather than relying solely on traditional methods like petri dishes.

What happened to the BreachForums website according to reports from October 10th?

The FBI announced they had seized the domains for the data leak and extortion site known as BreachForums, though operators of the site later claimed their operations remained unaffected.

Which event does the author plan to attend in 2025?

The author is planning to catch a few sessions at All Things Open 2025.

Jay Cuthrell October 12, 2025 Hot Fudge Sunday quantum

🌶️ Hot Fudge Sunday for 2025-10-12

Hot Fudge Daily digest for the week of 10-06-2025 to 10-11-2025.

Last Week

NexusTek published The Cybersecurity Awareness Month Challenge: Can Your Team Pass This Real-World Test?
Jason Pullo published Now Showing: Front Row for Hospitality IT’s Greatest Challenges
NexusTek published The Goldilocks Zone of Cyber Risk: Why Mid-Market Is “Just Right” for Hackers
Tyler Wrightson, Author and founder of Leet Cyber Security & Pavle Majerle (Moderator) published Think Like an Attacker: Building Cyber Defenses that Last

This Week

I am planning to catch a few sessions at All Things Open 2025.

Hot Fudge Daily Digest

📈 Markets Monday for 2025-10-06

🤖 🍪 🛰️ ₿ On Monday, the market moved once again for all things AI, chips, quantum, communications, and digital currency.

Symbol	Company Name	% Change
AMD	Advanced Micro Devices Inc	+19.16%
SANM	Sanmina Corp	+18.51%
IREN	IREN Ltd	+12.62%
PATH	UiPath Inc	+11.16%
RIOT	Riot Platforms Inc	+9.83%
ALAB	Astera Labs Inc	+9.09%
CLSK	CleanSpark Inc	+8.55%
MARA	Marathon Digital Holdings Inc	+8.51%
IONQ	IONQ Inc	+7.23%
ASTS	AST SpaceMobile Inc	+7.05%
BTDR	Bitdeer Technologies Group	+7.04%
FORM	FormFactor Inc	+6.77%
ASAN	Asana Inc	+6.51%
IRDM	Iridium Communications Inc	+6.29%
TWLO	Twilio Inc	+6.16%

🔥 Hot Takes Tuesday for 2025-10-07

💰 + 🤖 Funding for AI-anything companies continues.

FurtherAI (AI that automates insurance tasks): $25M
Bee Maps (decentralized AI dashcam mapping project): $32M
Heidi Health (AI for doctors and their admins): $65M
EvenUp (AI for law firms): $150M
xAI (AI platform): $20B

🤪 Wacky Wednesday for 2025-10-08

Trying a new format. Wacky. Wayback. Whoa.

First, a wacky wonderful video. Second, a wayback nostalgia tome. Third, a whoa we’re getting older moment.

Wacky Wonderful

DIY Phone

Soldering
Soliloquy
Satisfaction

Wayback

Internet History circa 2000)

FLASH! (AHHHHH! AHHHH!)
Slashdot Effect
P2P downloadin’

Whoa

Heat 2

Amazon Basics but for movie franchises
Anything might happen production
Age-gap casting for GenX

🔙 Throwback Thursday for 2025-10-09

Intel was in the new today.

2025

Today’s news is Intel’s massive 700 acres Arizona fab and the 18A process for Panther Lake chips. 🍪

2020

Five years ago, Intel was selling off memory and storage units. 💸

2015

A decade ago, Intel launched Skylake architecture and some might argue this is where the “tick-tock” reached the peak and then transformed to a countdown timer for the decade to come. ⏳

2010

Fifteen years back, Intel launched it’s “NVIDIA killer”. 😬

2005

Twenty years ago, Intel for better or for worse made “core” architecture, “number of cores”, and “core count” become a thing. 🔮

✅ Final Thoughts Friday for 2025-10-10

💊 + 🤖 The story that caught my eye this week was life sciences companies placing ever bigger bets on our new AI overlords.

The big story this week was AstraZeneca’s $555M deal to develop new drugs which signals a strategic shift from the petri dish alone to the processing core contribution as a catalyst. This isn’t about saving pennies on lab coats; it’s about compressing the multi-billion dollar, decade-long R&D cycle timeline into a high-speed computational augmented sprint.

The race (metaphor or otherwise) is on to see if the cure for what ails you is found in a molecule or an algorithm.

Of course, this shift also means that the attention to so-called “open” life sciences movements is increasingly important as AI computation is rapidly democratized to more than the best funded and already established life sciences companies.

🔮 Sneak Peak Saturday for 2025-10-11

Friday provided a classic trope from the world of cybersecurity that plays out with dependable regularity: The triumphant law enforcement takedown, immediately followed by the defiant criminal taunt.

Early Friday morning, a story broke that had all the hallmarks of a major victory for the good guys. The FBI announced it had seized the domains for BreachForums, a data leak and extortion site.

A big win, right? A decisive blow against the cyber bad guys.

Well, about that… the story comes with a punchline, just hours later, delivered by the cyber bad guys themselves… and they claim operations are “unaffected.”

It’s that familiar tale: law enforcement scores a point, but the game goes on. This story isn’t just about one or more domain seizures; it’s about the frustrating, asymmetric cyclical nature of the fight against cyber criminals, conveniently packaged for a day when fewer people are paying close attention.

#OpenToWork Weekly

I participated in a #NeverSearchAlone #JSC after rebooting Cuthrell Consulting and joining NexusTek.

I added those #OpenToWork from my LinkedIn network to this newsletter. Over time, we’ve grown an Alumni 🎉 section for those that transitioned to their next career adventure.